Angiogenesis Co-Culture Tube Formation
PrimeKit HUVEC Human Dermal Fibroblasts,
StemKit ECFCs and ADSCs

Cell Migration and Invasion
Scratch Wound Assays with or without biomatrices in a wide range of cell types

Cell Proliferation, Apoptosis, Cytotoxicty
Duplex/multiplexed with nuclear labels

NeuroTrack
TM
Neurite outgrowth - iPS-derived and primary neurons

• Reagent Generation

• Assay Development

• Hit Identification

• Hit-2-Lead-2-Candidate

• Mechanism of Action
Ion channel assay platforms including IonWorks Barracuda & Quattro automated electrophysiology, FLIPR Tetra & classical patch clamp.

Our Discovery Services business units offer contract research biology solutions for both ion channel drug discovery and safety, as well as live content imaging. We pride ourselves in our quality, flexibility, speed and customer focus. Our track record of introducing impactful, ground-breaking cell-based assay methodologies places our services division at the cutting edge. With over 100 years of drug discovery experience in our leadership team, and biologists who are technology and disease experts, we are uniquely positioned to provide specialized, customized solutions for our clients.

Fully kinetic, non-invasive 96/384 well imaging assays based around IncuCyte ZOOM and our CellPlayer reagents & assay protocols.  Fully validated for a wide range of cell types.
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Cardiac Safety Profiling:
hERG, hNav1.5, hCav1.2, hKv1.5, hKCNQ1+minK, Cav3.2,

Voltage-Gated Na+ Channels:
Nav1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8

Wide range of other assays/ion channel targets:
e.g.:TREK-1, Kv1.3, ICRAC, KCNQ2/3, Trpv1

Network of partners for fully-integrated solutions:
Please Inquire