IncuCyte Overview

INCUCYTE^TM Live-Cell Imaging System

The Essen IncuCyte family of products brings together a more efficient and thorough set of solutions for long-term, live-cell imaging. The IncuCyte imaging method allows you to expand the ways you document and understand cellular growth, behavior, and morphology. In addition, by design, it provides an effective kinetic read-out solution for the next generation of in vitro biological assays.

INCUBATORS AND MICROSCOPES: Like oil and water until now

In a paradigm shift, IncuCyte allows you to place a microscope inside your incubator, taking advantage of an asset you already own as well as eliminating any potential problems that may result from disturbing cells during the observation process. This IncuCyte approach makes long-term kinetic imaging convenient and affordable.

NEW CELLPLAYER^TM ASSAYS: Kinetic assays in your lab or ours

We have developed live-cell kinetic assays which incorporate the latest biological models, time-lapse recording, and integrated image processing algorithms into a complete set of solutions called CellPlayer^TM Assays. These assay solutions can be run by you in your laboratory, or we can run them for you as a service. To date, our CellPlayer^TM Assays are comprised of functional read-outs of cell migration and co-culture angiogenesis.

HD IMAGING: High-quality phase-contrast imaging in microplates

Historically, phase-contrast imaging in 96 and 384-well microplates has been hampered by aberrations caused by the fluid meniscus in the well. HD Imaging, a proprietary imaging format developed by Essen BioScience specifically for IncuCyte, is insensitive to these aberrations. HD imaging greatly enhances phase-contrast imaging in microplates enabling applications such as cell plating quality control and non-labeled proliferation studies.

VESSEL CAPACITY: IncuCyte supports hundreds of cell culture vessels

The IncuCyte is designed with increased productivity in mind supporting hundreds of standard varieties of cell culture vessels, including 96- and 384-well plates, T-flasks, dishes, and micro-slides. With three configurable trays, you can mix and match multiple vessels and even monitor different experiments running concurrently. Image location and timing of acquisition are controlled by the user, and access to the kinetic image history is supported via an image database and retrieval system.

List of IncuCyte-supported vessels

Software and Interface: Intuitive design and easy access

Based on a client-server methodology, the interface enables you to acquire, access, and analyze information from any computer on the local network. The software is also designed to make it simple to retrieve information either chronologically or by experiment and user can easily create movies from captured images - all of which are exportable in a number of formats.